Table 6P.2f - Detailed data analysis for cases reporting laser interstitial thermal therapy (LITT) of brain in MS-DRG 040																																			
Case Number 	Principal Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 	Secondary Diagnosis 		Procedure 	Procedure 	Procedure 	Procedure 	Procedure 	Procedure 	Procedure 	Procedure 	Procedure 
1	D32.0 Benign neoplasm of cerebral meninges	G93.6 Cerebral edema	"R00.1 Bradycardia, unspecified"	Z20.822 Contact with and (suspected) exposure to COVID-19	G93.5 Compression of brain	E27.40 Unspecified adrenocortical insufficiency	E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	G50.0 Trigeminal neuralgia	I10 Essential (primary) hypertension	"E11.40 Type 2 diabetes mellitus with diabetic neuropathy, unspecified"	R56.9 Unspecified convulsions	K21.9 Gastro-esophageal reflux disease without esophagitis	G89.29 Other chronic pain	"F32.9 Major depressive disorder, single episode, unspecified"	"D72.829 Elevated white blood cell count, unspecified"	G93.89 Other specified disorders of brain	Z86.16 Personal history of COVID-19	Z79.52 Long term (current) use of systemic steroids	Z79.4 Long term (current) use of insulin	Z98.2 Presence of cerebrospinal fluid drainage device							D0Y0KZZ Laser interstitial thermal therapy of brain								
2	C79.31 Secondary malignant neoplasm of brain	G93.6 Cerebral edema	C79.51 Secondary malignant neoplasm of bone	E44.0 Moderate protein-calorie malnutrition	"E78.5 Hyperlipidemia, unspecified"	R47.1 Dysarthria and anarthria	"R13.10 Dysphagia, unspecified"	H53.2 Diplopia	R27.8 Other lack of coordination	"R11.2 Nausea with vomiting, unspecified"	"N18.2 Chronic kidney disease, stage 2 (mild)"	"Z68.21 Body mass index [BMI] 21.0-21.9, adult"	Z85.3 Personal history of malignant neoplasm of breast	Z92.21 Personal history of antineoplastic chemotherapy	Z92.3 Personal history of irradiation	Z90.10 Acquired absence of unspecified breast and nipple	Z90.49 Acquired absence of other specified parts of digestive tract	Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels	Z79.83 Long term (current) use of bisphosphonates	Z88.0 Allergy status to penicillin	Z80.42 Family history of malignant neoplasm of prostate	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain								
3	C71.1 Malignant neoplasm of frontal lobe	J69.0 Pneumonitis due to inhalation of food and vomit	G93.5 Compression of brain	G93.6 Cerebral edema	"I61.1 Nontraumatic intracerebral hemorrhage in hemisphere, cortical"	J96.01 Acute respiratory failure with hypoxia	D68.8 Other specified coagulation defects	"I82.443 Acute embolism and thrombosis of tibial vein, bilateral"	I82.451 Acute embolism and thrombosis of right peroneal vein	I82.431 Acute embolism and thrombosis of right popliteal vein	I82.411 Acute embolism and thrombosis of right femoral vein	R47.01 Aphasia	"G81.91 Hemiplegia, unspecified affecting right dominant side"	G91.1 Obstructive hydrocephalus	"K92.2 Gastrointestinal hemorrhage, unspecified"	I82.461 Acute embolism and thrombosis of right calf muscular vein	I10 Essential (primary) hypertension	"E66.9 Obesity, unspecified"	G93.89 Other specified disorders of brain	Z92.21 Personal history of antineoplastic chemotherapy	Z92.3 Personal history of irradiation	"D64.9 Anemia, unspecified"	"D69.6 Thrombocytopenia, unspecified"	R31.0 Gross hematuria	"K59.00 Constipation, unspecified"		D0Y0KZZ Laser interstitial thermal therapy of brain	"4A10X4Z Monitoring of central nervous electrical activity, external approach"	"02HV33Z Insertion of infusion device into superior vena cava, percutaneous approach"	"B548ZZA Ultrasonography of superior vena cava, guidance"	"03HY32Z Insertion of monitoring device into upper artery, percutaneous approach"	"06H03DZ Insertion of intraluminal device into inferior vena cava, percutaneous approach"	"5A1945Z Respiratory ventilation, 24-96 consecutive hours"	"0BH17EZ Insertion of endotracheal airway into trachea, via natural or artificial opening"	"0DH63UZ Insertion of feeding device into stomach, percutaneous approach"
4	"C71.9 Malignant neoplasm of brain, unspecified"	Z00.6 Encounter for examination for normal comparison and control in clinical research program	G93.6 Cerebral edema	Z51.5 Encounter for palliative care	"D64.9 Anemia, unspecified"	"J45.909 Unspecified asthma, uncomplicated"	Z92.21 Personal history of antineoplastic chemotherapy	Z92.3 Personal history of irradiation	Z85.3 Personal history of malignant neoplasm of breast	K21.9 Gastro-esophageal reflux disease without esophagitis	Z20.822 Contact with and (suspected) exposure to COVID-19	R60.0 Localized edema	"M79.2 Neuralgia and neuritis, unspecified"	"R33.9 Retention of urine, unspecified"	"R73.9 Hyperglycemia, unspecified"	"T38.0X5A Adverse effect of glucocorticoids and synthetic analogues, initial encounter"	"K59.00 Constipation, unspecified"	"G47.00 Insomnia, unspecified"	"G31.84 Mild cognitive impairment, so stated"	R74.01 Elevation of levels of liver transaminase levels	R23.3 Spontaneous ecchymoses	"S80.822A Blister (nonthermal), left lower leg, initial encounter"	"K71.10 Toxic liver disease with hepatic necrosis, without coma"	"R41.0 Disorientation, unspecified"	R54 Age-related physical debility		D0Y0KZZ Laser interstitial thermal therapy of brain	D0Y08ZZ Hyperthermia of brain							
5	"C71.9 Malignant neoplasm of brain, unspecified"	J96.01 Acute respiratory failure with hypoxia	G93.89 Other specified disorders of brain	K21.9 Gastro-esophageal reflux disease without esophagitis	I10 Essential (primary) hypertension	"E03.9 Hypothyroidism, unspecified"	R56.9 Unspecified convulsions	Z88.6 Allergy status to analgesic agent	Z86.011 Personal history of benign neoplasm of the brain	Z00.6 Encounter for examination for normal comparison and control in clinical research program	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain	"03HY32Z Insertion of monitoring device into upper artery, percutaneous approach"							
6	C71.4 Malignant neoplasm of occipital lobe	G93.5 Compression of brain	G93.6 Cerebral edema	"G51.32 Clonic hemifacial spasm, left"	I10 Essential (primary) hypertension	"E78.00 Pure hypercholesterolemia, unspecified"	Z85.46 Personal history of malignant neoplasm of prostate	Z87.891 Personal history of nicotine dependence	Z79.899 Other long term (current) drug therapy	Z96.652 Presence of left artificial knee joint	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain	"8E093CZ Robotic assisted procedure of head and neck region, percutaneous approach"							
7	C79.31 Secondary malignant neoplasm of brain	G93.6 Cerebral edema	G93.5 Compression of brain	"J45.909 Unspecified asthma, uncomplicated"	Z85.3 Personal history of malignant neoplasm of breast	Z92.3 Personal history of irradiation	"Z88.8 Allergy status to other drugs, medicaments and biological substances"	Z91.013 Allergy to seafood	Z80.3 Family history of malignant neoplasm of breast	Z80.49 Family history of malignant neoplasm of other genital organs	"Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung"	Z82.49 Family history of ischemic heart disease and other diseases of the circulatory system	 	 	 	 	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain	"8E093CZ Robotic assisted procedure of head and neck region, percutaneous approach"							
8	"C71.9 Malignant neoplasm of brain, unspecified"	J96.01 Acute respiratory failure with hypoxia	I10 Essential (primary) hypertension	"E16.2 Hypoglycemia, unspecified"	"D72.829 Elevated white blood cell count, unspecified"	K21.9 Gastro-esophageal reflux disease without esophagitis	Z88.0 Allergy status to penicillin	Z88.7 Allergy status to serum and vaccine	"Z88.8 Allergy status to other drugs, medicaments and biological substances"	Z87.891 Personal history of nicotine dependence	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain								
9	C79.31 Secondary malignant neoplasm of brain	G93.6 Cerebral edema	G93.5 Compression of brain	D61.810 Antineoplastic chemotherapy induced pancytopenia	C79.51 Secondary malignant neoplasm of bone	E27.40 Unspecified adrenocortical insufficiency	E44.0 Moderate protein-calorie malnutrition	E87.0 Hyperosmolality and hypernatremia	Z20.822 Contact with and (suspected) exposure to COVID-19	"T45.1X5A Adverse effect of antineoplastic and immunosuppressive drugs, initial encounter"	C50.919 Malignant neoplasm of unspecified site of unspecified female breast	"I95.9 Hypotension, unspecified"	"R19.7 Diarrhea, unspecified"	E87.6 Hypokalemia	"R00.1 Bradycardia, unspecified"	Z92.21 Personal history of antineoplastic chemotherapy	"Z68.23 Body mass index [BMI] 23.0-23.9, adult"	Z90.89 Acquired absence of other organs	Z92.3 Personal history of irradiation	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain								
10	"C71.9 Malignant neoplasm of brain, unspecified"	G93.6 Cerebral edema	D63.1 Anemia in chronic kidney disease	"E66.9 Obesity, unspecified"	"Z68.34 Body mass index [BMI] 34.0-34.9, adult"	"I12.9 Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease"	K21.9 Gastro-esophageal reflux disease without esophagitis	M81.0 Age-related osteoporosis without current pathological fracture	"N18.30 Chronic kidney disease, stage 3 unspecified"	Z87.442 Personal history of urinary calculi	Z96.611 Presence of right artificial shoulder joint	Z98.1 Arthrodesis status	"H57.11 Ocular pain, right eye"	 	 	 	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain	2W30XYZ Immobilization of head using other device							
11	C79.31 Secondary malignant neoplasm of brain	G93.6 Cerebral edema	C34.92 Malignant neoplasm of unspecified part of left bronchus or lung	C79.72 Secondary malignant neoplasm of left adrenal gland	C79.71 Secondary malignant neoplasm of right adrenal gland	"J43.9 Emphysema, unspecified"	"F32.9 Major depressive disorder, single episode, unspecified"	R29.810 Facial weakness	R47.1 Dysarthria and anarthria	"F41.9 Anxiety disorder, unspecified"	R47.81 Slurred speech	Z87.891 Personal history of nicotine dependence	Z90.2 Acquired absence of lung [part of]	Z92.3 Personal history of irradiation	Z79.899 Other long term (current) drug therapy	Z86.711 Personal history of pulmonary embolism	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain								
12	C79.31 Secondary malignant neoplasm of brain	G93.6 Cerebral edema	"N17.9 Acute kidney failure, unspecified"	G72.0 Drug-induced myopathy	I67.89 Other cerebrovascular disease	R91.1 Solitary pulmonary nodule	E11.65 Type 2 diabetes mellitus with hyperglycemia	I69.344 Monoplegia of lower limb following cerebral infarction affecting left non-dominant side	Z20.822 Contact with and (suspected) exposure to COVID-19	Z85.51 Personal history of malignant neoplasm of bladder	Z85.820 Personal history of malignant melanoma of skin	"T38.0X5A Adverse effect of glucocorticoids and synthetic analogues, initial encounter"	Z91.040 Latex allergy status	Z88.0 Allergy status to penicillin	Z79.4 Long term (current) use of insulin	I10 Essential (primary) hypertension	Z90.49 Acquired absence of other specified parts of digestive tract	Z85.46 Personal history of malignant neoplasm of prostate	Z80.41 Family history of malignant neoplasm of ovary	Z80.0 Family history of malignant neoplasm of digestive organs	Z87.19 Personal history of other diseases of the digestive system	"D69.6 Thrombocytopenia, unspecified"	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain								
13	C79.31 Secondary malignant neoplasm of brain	G93.5 Compression of brain	J69.0 Pneumonitis due to inhalation of food and vomit	"G81.94 Hemiplegia, unspecified affecting left nondominant side"	I24.8 Other forms of acute ischemic heart disease	"T17.890A Other foreign object in other parts of respiratory tract causing asphyxiation, initial encounter"	I97.3 Postprocedural hypertension	"J43.9 Emphysema, unspecified"	Z20.822 Contact with and (suspected) exposure to COVID-19	Z87.891 Personal history of nicotine dependence	Z85.038 Personal history of other malignant neoplasm of large intestine	Z85.118 Personal history of other malignant neoplasm of bronchus and lung	Z92.21 Personal history of antineoplastic chemotherapy	Z87.892 Personal history of anaphylaxis	Z88.1 Allergy status to other antibiotic agents	"Z88.8 Allergy status to other drugs, medicaments and biological substances"	Z92.3 Personal history of irradiation	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain	"00993ZX Drainage of thalamus, percutaneous approach, diagnostic"	8E09XBZ Computer assisted procedure of head and neck region	"8E093CZ Robotic assisted procedure of head and neck region, percutaneous approach"	B030YZZ Magnetic resonance imaging (MRI) of brain using other contrast	"B030Y0Z Magnetic resonance imaging (MRI) of brain using other contrast, unenhanced and enhanced"	B246ZZZ Ultrasonography of right and left heart		
14	C79.31 Secondary malignant neoplasm of brain	G93.6 Cerebral edema	C78.00 Secondary malignant neoplasm of unspecified lung	C79.51 Secondary malignant neoplasm of bone	I67.89 Other cerebrovascular disease	"E03.9 Hypothyroidism, unspecified"	G89.3 Neoplasm related pain (acute) (chronic)	"J44.9 Chronic obstructive pulmonary disease, unspecified"	G58.8 Other specified mononeuropathies	"M54.9 Dorsalgia, unspecified"	C43.59 Malignant melanoma of other part of trunk	Z87.891 Personal history of nicotine dependence	Z92.21 Personal history of antineoplastic chemotherapy	 	 	 	 	 	 	 	 	 	 	 	 		D0Y0KZZ Laser interstitial thermal therapy of brain								
																																			
																																			
	Notes:																																		
	"For the associated severity level designations (CC or MCC) for the secondary diagnoses listed, we refer the reader to the V39.1 ICD-10 MS-DRG Definitions Manual (Appendix G and Appendix H), available via the internet on the CMS web page at: https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/AcuteInpatientPPS/MS-DRG-Classifications-and-Software"																																		
